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In males, testosterone is responsible for many normal functions, including growth and development of the genitals, muscles, and bones. Symptoms of human growth hormone deficiency include depression, fatigue, decreased muscle strength and mass, insulin resistance, hair loss, cardiovascular disease risk, memory loss, and delayed puberty in children.

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Increasing the dose through a cycle (pyramiding) may result in doses 5 to 100 times the physiologic dose.

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